Incomplete biomarker testing can lead to inappropriate treatment selection

Fewer than 20% of advanced NSCLC patients get complete guideline-recommended biomarker testing9

10

The number of biomarkers guidelines recommend testing advanced NSCLC patients for before treatment

The list of biomarkers that are matched with an FDA-approved targeted therapy is growing.

EGFR

KRAS

ALK

ROS1

BRAF

MET

RET

ERBB2

NTRK

PD-L1

2 in 3 NSCLC patients

have a biomarker that can be targeted with available therapies10

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Matching advanced NSCLC patients to targeted therapy using biomarker testing results improves outcomes11

Sotorasib (LUMAKRAS)18 significantly
increases PFS compared to docetaxel11

Sotorasib targets KRAS G12C, one of the most common NSCLC biomarkers. 1 in 8 patients with advanced lung cancer has a KRAS G12C mutation.10

Advanced NSCLC patients with targetable mutations should not be treated with immunotherapy1

82%

of NSCLC patients could get the wrong treatment because their doctors fail to order complete biomarker testing.9

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One chance to make the right decision

There may be just one opportunity for a doctor to make the right decision about a patient’s first-line treatment for advanced NSCLC.

Only 1 in 2 NSCLC patients make it to receive second-line therapy15, 16